All research activity at Royal Papworth Hospital is conducted in accordance with Trust approved Standard Operating Procedures (SOPs) which are available to view by clicking on the individual titles of the SOPs in the list below.

Please find attached here a routemap which shows a timelime of SOPs used for clinical trials.

The SOP Committee meets regularly to design and review the SOPs. For more information please email Vikki Hughes
Please note that forms, guidelines, templates and information sheets are available on the guidance documents, templates and forms page.

New SOP's for Review:

SOP 037 Amendments to Research Studies

SOP 038 Change of Investigator

SOP 073 Sourcing of Investigational Medicinal Products for Papworth Sponsored Studies



The standard operating procedures relating to PTUC can be found below by searching for PTUC.  They will have PTUC in the 'Tags' column.

The following SOPs apply to both PTUC and R&D:

SOP 001 Production Approval and Review of SOPs

SOP 002 Training Records for Research Active Staff





Title Tags Description
SOP099 HLRI CRF Medical cover v2 .pdf SOP099 HLRI CFR Medical Cover for Research Studies SOP099 HLRI CRF Medical Cover for Research Studies
SOP098_Pipetting__v1.0.pdf SOP098 Pipetting SOP098 Pipetting
SOP096_Centrifugation_v2.0 Signed.pdf Centrifugation SOP096 CRF SOP096 Centrifugation
SOP_092_-_Research_Account_Management_-_Final..docx.pdf SOP092 Research Account Management
SOP088 Clinical Trial Participants and Pregnancy.pdf R&D SOP088
SOP086 Electronic Signature.pdf R&D SOP086
SOP085 Monitoring Research Studies - External Monitors and Remote Monitoring.pdf R&D SOP085
SOP084 Direct to Patient Delivery of IMP version 1.0 FINAL.pdf R&D SOP084
SOP082 Returns of IMP to Pharmacy.pdf R&D SOP082
Destruction of Waste IMP (Investigational Medicinal Product) (SOP081).pdf R&D SOP081
Study Data - Collection and Entry (SOP080).pdf PTUC SOP080
Reference Safety Information (RSI) (SOP 079).pdf PTUC SOP079
Data Management Plan (SOP078).pdf PTUC SOP078
Data Management Overview (SOP 077).pdf PTUC SOP077
Transport, Storage and Enviromental Monitoring of IMP's (SOP 076).pdf R&D SOP076
SOP075 Quarantine of IMP's (Investigational Medicinal Products).pdf PTUC SOP075
Handling of Drug Alerts and Recalls of Investigational Medicinal Products (IMPs) or other trial related drugs (SOP074).pdf R&D SOP074
Sourcing of Investigational Medicinal Products for Papworth Sponsored Studies Manufacturing, Assembly and Labelling (SOP073).pdf PTUC SOP073
Supply of Clinical Trials Investigational Medicinal Products (IMP) Dispensing Returns and Accountability (SOP 072).pdf PTUC SOP072
Urgent Safety Measures (SOP 071).pdf PTUC SOP071