Heart research

Cardiac Surgery
Cardiology: Interventional, Medicinal, Observational
  • CRAFT: Cryoballoon Pulmonary Vein Isolation as First Line Treatment for Typical Atrial Flutter. PI Dr C Martin. Sponsor: Liverpool Heart and Chest Hospital https://clinicaltrials.gov/ct2/show/NCT03401099
  • COHORT substudy: Minimally-invasive phenotyping of arrhythmias in idiopathic pulmonary arterial hypertension. A sub-study of the National Cohort study of Idiopathic and Heritable Pulmonary Arterial Hypertension. PI Dr C Martin and Dr M Toshner. Sponsor: Royal Papworth Hospital NHS Foundation Trust http://www.ipahcohort.com/
  • PRAETORIAN-DFT: A Prospective Randomised Comparative trial of Subcutaneous Implantable Cardioverter-Defibrillator Implantation with and without Defibrillation Testing. CI Dr C Martin. Sponsor: Academic Medical Center, Amsterdam, the Netherlands https://clinicaltrials.gov/ct2/show/NCT03495297
  • INTERRUPT-AF: Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal Atrial Fibrillation. CI Dr C Martin. Sponsor: Boston Scientific https://clinicaltrials.gov/ct2/show/NCT03729830

Lung research

Lung Cancers
  • TIDAL: Feasibility Study to Estimate Number of Patients With Precancerous Areas in Their Airways and the Response to Gefitinib (TIDAL1), Sponsor: Papworth Hospital NHS Foundation Trust

CI Prof T Eisen Click here for further information and Here

  • Approaches to earlier detection & intervention in lung cancer-Study 1a. UKCRN ID 14157
  • MARS2: A study to determine if it is feasible to recruit into a randomised trial comparing (extended) pleurectomy decortication versus no pleurectomy decortication in the multimodality management of patients with malignant pleural mesothelioma. UKCRN ID 15909. Click here for Further Information;CI Mr E Lim, Sponsor: Royal Brompton & Harefield NHS Trust
  • MESOTRAP: A feasibility study comparing video-assisted thoracoscopic partial pleurectomy/decortication with indwelling pleural catheter in patients with trapped lung due to malignant pleural mesothelioma designed to address recruitment and randomisation uncertainties and sample size requirements for a phase III trial. Click here for further information. CI Dr R Rintoul, Sponsor: Papworth Hospital NHS Foundation Trust
Sleep Disorders
  • MIMOSA Study: Effect of acute intravenous morphine administration on Sleep Disordered Breathing (SDB) and sleep architecture in patients with moderate Obstructive Sleep Apnoea (OSA): A randomised controlled trial. CI Dr Ian Smith, Sponsor: Papworth Hospital NHS Foundation Trust. Further information                                                                                                                                                           
  • POSAG Trial: Prevalence of Obstructive Sleep Apnoea in Glaucoma    Prospective observational controlled trial of the prevalence of obstructive sleep apnoea in patients with open­ angle glaucoma. Sponsor: Papworth Hospital NHS Foundation Trust, CI Dr Ian Smith, PI Dr Dariusz Wozniak, Contact for further information
  • PAIR Study Intraocular pressure changes in response to continuous positive airway pressure during diurnal trial in people with treated primary open-angle glaucoma, treatment naïve primary open-angle glaucoma patients and control subjects. Sponsor: Papworth Hospital NHS Foundation Trust. CI Dr Ian Smith.  Further information
  • PCOSA-1: PFO closure for obstructive sleep apnoea. Please click here for further information


Pulmonary Hypertension
Cystic Fibrosis


  • ReCliC: The Repurposing of Clinical Data for Quality Improvement in Critical Care. Click HERE for further information. CI: Dr M Jones, Sponsors: Papworth NHS Hospital Foundation Trust and the University of Cambridge

Where are we based?

Royal Papworth Hospital NHS Foundation Trust
Papworth Road
Cambridge Biomedical Campus

Telephone:  01223 638000

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