Dr Alain Vuylsteke is the Clinical Director of the Division of Surgery, Transplantation and Anaesthesia 

He has been a Consultant in Cardiothoracic Anaesthesia and Intensive Care Medicine at Papworth since 1998, and has been Director of the National Respiratory ECMO Service at Papworth since 2011.

Prior to taking on the role of Clinical Director, Dr Vuylsteke spent four years as director of the Intensive Care Unit, and four years as the Chair of the Hospital Drugs and Therapeutics Committee.

Outside Papworth, Dr Vuylsteke is an Associate Lecturer at the University of Cambridge and an examiner for the Faculty of Intensive Care Medicine.He is a member of the Adult Critical Care Clinical Reference Group.

His clinical interests include Extracorporeal Membrane Oxygenation (ECMO), the use of mechanical assist devices and the impact of IT on healthcare. He has supported a wide portfolio of clinical research over the years, as well as fundamental projects related to his clinical work.



Intensive care

Specialist Clinical Interests

Extracorporeal Membrane Oxygenation (ECMO)
Cardiothoracic Intensive Care
Impact of IT on healthcare

Special research Interests

Facilitator of multiple projects related to his clinical work
Impact of IT on healthcare


Currently or formerly acting as investigator or scientific advisor for, or having received fees for consultancy from the following companies: Abbott, Adprotech, Aortech, AstraZeneca, Baxter Hemoglobin Therapeutics, CERT (China), CSL Behring, Elan Pharma, EMS Research, e-Rewards, GLG Group, Hemosol, Esai, Genzyme, Junicon, Medefield, Medicys, NovoNordisk, Pharmacia & Upjohn, Procter & Gable, Searle, The Medicines Company.

Education and Training

Bachelor of Science - BSc 1987
Doctor of Medicine - MD 1991
Certificate of Completion of Specialist Training - CCST(Anaesthesia) 1998
Diplôme d'Enseignement Spécialisé en Anésthesie at Réanimation - DESAR 1998
Fellow of the Royal College of Anaesthetists - FRCA 2004
Fellow of the Faculty of Intensive Care Medicine, FFICM 2011
Master of Arts, University of Cambridge - MA 2014

Current membership(s) of professional, national and regional bodies and university posts

University of Cambridge, Associate Lecturer
FICM, Examiner
Adult Critical Care Clinical Reference Group, Clinical Member

Recent Publications

Publications listed on Google Scholar

20 most cited papers
MA Noah, GJ Peek, SJ Finney, MJ Griffiths, DA Harrison, R Grieve. Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A (H1N1) Jama 306 (15), 1659-1668, 2011

DT Mangano, Y Miao, A Vuylsteke, IC Tudor, R Juneja, D Filipescu. Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery ... JAMA: the journal of the American Medical Association 297 (5), 471 2007

A Combes, D Brodie, R Bartlett, L Brochard, R Brower, S Conrad. Position paper for the organization of extracorporeal membrane oxygenation programs for acute respiratory failure in adult patients. American journal of respiratory and critical care medicine 190 (5), 488-496 2014

R Gill, M Herbertson, A Vuylsteke, PS Olsen, C von Heymann, M Mythen. Safety and Efficacy of Recombinant Activated Factor VII ... Circulation 120 (1), 21-27 2009

DT Mangano. Multicenter study of perioperative ischemia research group; Ischemia Research and Education Foundation. The risk associated with aprotinin in cardiac surgery.  N Engl J Med. 354, 353-365 2006

M Berman, S Tsui, A Vuylsteke, A Snell, S Colah, R Latimer, R Hall. Successful extracorporeal membrane oxygenation support after pulmonary thromboendarterectomy. The Annals of Thoracic Surgery 86 (4), 1261-1267 2008

A Vuylsteke, L Sharples, G Charman, J Kneeshaw, S Tsui, J Dunning. Circulatory arrest versus cerebral perfusion during pulmonary endarterectomy surgery (PEACOG): a randomised controlled trial. The Lancet 378 (9800), 1379-1387 2011

D Abrams, AR Garan, A Abdelbary, M Bacchetta, RH Bartlett, J Beck. Position paper for the organization of ECMO programs for cardiac failure in adults. Intensive care medicine 44 (6), 717-729 2018

A Vuylsteke, C Pagel, C Gerrard, B Reddy, S Nashef, P Aldam, M Utley. The Papworth Bleeding Risk Score: a stratification scheme for identifying cardiac surgery patients at risk of excessive early postoperative bleeding. European journal of cardio-thoracic surgery 39 (6), 924-930 2011

CK Choong, C Gerrard, KA Goldsmith, H Dunningham, A Vuylsteke. Delayed re-exploration for bleeding after coronary artery bypass surgery results in adverse outcomes.  European journal of cardio-thoracic surgery 31 (5), 834 2007

HO Yusuff, V Zochios, A Vuylsteke. Extracorporeal membrane oxygenation in acute massive pulmonary embolism: a systematic review. Perfusion 30 (8), 611-616 2015

AVV Powroznyk, A Vuylsteke, C Naughton, SL Misso, J Holloway Comparison of clevidipine with sodium nitroprusside in the control of blood pressure after coronary artery surgery. European Journal of Anaesthesiology (EJA) 20 (9), 697-703 2003

AA Klein, SAM Nashef, L Sharples, F Bottrill, M Dyer, J Armstrong. A randomized controlled trial of cell salvage in routine cardiac surgery. Anesthesia & Analgesia 107 (5), 1487 2008

C Morrison, M Jones, A Blackwell, A Vuylsteke. Electronic patient record use during ward rounds: a qualitative study of interaction between medical staff. Critical Care 12 (6), R148 2008

B Thomson, SSL Tsui, J Dunning, A Goodwin, A Vuylsteke, R Latimer. Pulmonary endarterectomy is possible and effective without the use of complete circulatory arrest--the UK experience in over 150 patients. European Journal of Cardio-Thoracic Surgery 33 (2), 157 2008

X Guo, E Kuzumi, SC Charman, A Vuylsteke. Perioperative melatonin secretion in patients undergoing coronary artery bypass grafting. Anesthesia & Analgesia 94 (5), 1085 2002

A Vuylsteke, A Oduro, E Cardan, RD Latimer. Effect of aspirin in coronary artery bypass grafting. Journal of cardiothoracic and vascular anesthesia 11 (7), 831-834    1997

DCH Cheng, CD Mazer, R Martineau, A Ralph-Edwards, J Karski. A phase II dose-response study of hemoglobin raffimer (Hemolink) in elective coronary artery bypass surgery.The Journal of Thoracic and Cardiovascular Surgery 127 (1), 79-86 2004

CDR Borland, H Dunningham, F Bottrill, A Vuylsteke, C Yilmaz, DM Dane. Significant blood resistance to nitric oxide transfer in the lung. Journal of applied physiology 108 (5), 1052-1060 2010

A Combes, D Brodie, YS Chen, E Fan, JPS Henriques, C Hodgson. The ICM research agenda on extracorporeal life support. Intensive care medicine 43 (9), 1306-1318  

More publications available at PubMed.