Dr Martin was appointed as a Consultant Electrophysiologist at Royal Papworth in 2018, and is also assistant director of research and development at Royal Papworth and an affiliated assistant professor at the University of Cambridge.
She undertook undergraduate and clinical training at Cambridge University (Gonville and Caius College). Dr Martin completed a PhD at the University of Cambridge funded by a Medical Research Council Training Fellowship, and for this was awarded the British Cardiovascular Society Young Research Workers' Prize. After specialist training at Papworth Hospital, she undertook clinical fellowships at two world-leading cardiac centres: Barts Heart Centre and subsequently at the Hopital du Haut-Leveque, Bordeaux, through funding from a prestigious European Society of Cardiology Training Grant.
Dr Martin treats all cardiac arrhythmias, and has a particular interest in the ablation of ventricular tachycardia and atrial fibrillation. See clairemartincardiologist.com and cardiovascular.cam.ac.uk for further details of her research interests.
- Arrhythmias
- Catheter ablation of ventricular tachycardia
- Atrial tachycardia and atrial fibrillation
- Inherited arrhythmia syndromes
Mechanisms and ablation strategies for ventricular tachycardia, atrial tachycardia and atrial fibrillation; mechanisms and risk stratification in inherited arrhythmia syndromes
- MA Natural Sciences, University of Cambridge 2001
- MB BChir, University of Cambridge 2004
- MRCP, London 2007
- PhD Cardiac Electrophysiology, University of Cambridge 2012
- British Heart Rhythm Accreditation in Devices and Electrophysiology 2016
- Affiliated Assistant Professor, University of Cambridge
- Member of the Royal College of Physicians, London.
- Member of the General Medical Council (registration number: 6110131).
- Honorary Research Fellow, University College London and Bordeaux University
- Member of British Heart Rhythm Society
- Member of British Cardiac Society
- Member of European Society of Cardiology
Full list of peer-reviewed publications by Dr Martin are available on Google Scholar » and PubMed »
Book chapters
1. Martin CA and Lambiase PD (2018). Atrial fibrillation and progressive cardiac conduction disease. In: Cardiovascular Genetics and Genomics for Clinicians. Eds. Kumar D; Elliott, P DOI 10.1007/978-3-319-66114-8_15
Original research articles
1. Knops RE, El-Chami MF, Marquie C, Nordbeck P, Quast ABE, Tilz RR, Brouwer TF, Lambiase PD, Cassidy CJ, Boersma LVA, Burke MC, Pepplinkhuizen S, de Veld JA, de Weger A, Bracke FALE, Manyam H, Probst V, Betts TR, Bijsterveld NR, Defaye P, Demming T, Elders J, Field DC, Ghani A, Golovchiner G, de Jong JSSG, Lewis N, Marijon E, Martin CA, Miller MA, Shaik NA, van der Stuijt W, Kuschyk J, Olde Nordkamp LRA, Arya A, Borger van der Burg AE, Boveda S, van Doorn DJ, Glikson M, Kaiser L, Maass AH, van Woerkens LJPM, Zaidi A, Wilde AAM, Smeding L. The predictive value of the PRAETORIAN score for defibrillation test success in subcutaneous ICD patients: a sub-analysis of the PRAETORIAN-DFT trial. Heart Rhythm. 2024 Feb 7:S1547-5271(24)00115-2. doi: 10.1016/j.hrthm.2024.02.005.
2. Maclean E, Mahtani K, Honarbakhsh S, Butcher C, Ahluwalia N, Dennis ASC, Creta A, Finlay M, Elliott M, Mehta V, Wijesuriya N, Shaikh O, Zaw Y, Ogbedeh C, Gautam V, Lambiase PD, Schilling RJ, Earley MJ, Moore P, Muthumala A, Sporton SEC, Hunter RJ, Rinaldi CA, Behar J, Martin C, Monkhouse C, Chow A. Blister Score: A Novel, Externally Validated Tool for Predicting Cardiac Implantable Electronic Device Infections, and Its Cost-Utility Implications for Antimicrobial Envelope Use. Circ Arrhythm Electrophysiol. 2024 Jan 22:e012446. doi: 10.1161/CIRCEP.123.012446
3. Butcher C, Rajappan S, Wharmby AL, Ullah W, Wong T, Jones D, Rajappan K, Martin C, Elliott P, Gill JS, Specterman M, Dhinoja MB, Sporton S, Lambiase PD, Hunter RJ, Honarbakhsh S. Atrioventricular nodal ablation is an effective management strategy for atrial fibrillation in patients with hypertrophic cardiomyopathy.Heart Rhythm. 2023 Dec;20(12):1606-1614. doi: 10.1016/j.hrthm.2023.08.028.
4. Ikenouchi T, Takigawa M, Goya M, Yamaguchi J, Martin CA, Yamamoto T, Negishi M, Kawamura I, Goto K, Shigeta T, Nishimura T, Takamiya T, Tao S, Miyazaki S, Sasano T. The effect of half-normal saline irrigation on lesion characteristics in temperature-flow-controlled ablation. J Interv Card Electrophysiol. 2023 Nov 9. doi: 10.1007/s10840-023-01678-7
5. Iwakawa H, Takigawa M, Yamaguchi J, Martin CA, Goya M, Yamamoto T, Amemiya M, Ikenouchi T, Negishi M, Kawamura I, Goto K, Shigeta T, Nishimura T, Takamiya T, Tao S, Miyazaki S, Watanabe H, Sasano T. Superiority of the Combination of Input and Output Parameters to the Single Parameter for Lesion Size Estimation. Circ J. 2023 Nov 24;87(12):1757-1764. doi: 10.1253/circj.CJ-23-0574.
6. Honarbakhsh S, Martin CA, Mesquita J, Herlekar R, Till R, Srinivasan NT, Duncan E, Leong F, Dulai R, Veasey R, Panikker S, Paisey J, Ramgopal B, Das M, Ahmed W, Sahu J, Earley MJ, Finlay MC, Schilling RJ, Hunter RJ. Atrial fibrillation cryoablation is an effective day case treatment: the UK PolarX vs. Arctic Front Advance experience. Europace. 2023 Nov 2;25(11):euad286. doi: 10.1093/europace/euad286.
7. Takigawa M, Sacher F, Martin C, Cheniti G, Duchateau J, Pambrun T, Derval N, Cochet H, Hocini M, Yamamoto T, Nishimura T, Tao S, Miyazaki S, Goya M, Sasano T, Haissaguierre M, Jais P. Impact of filter configurations on bipolar EGMs: An optimal filter setting for identifying VT substrates. .J Cardiovasc Electrophysiol. 2023 Jul 11. doi: 10.1111/jce.15997
8. Takigawa M, Kamakura T, Martin C, Derval N, Cheniti G, Duchateau J, Pambrun T, Sacher F, Cochet H, Hocini M, Negishi M, Yamamoto T, Ikenouchi T, Goto K, Shigeta T, Nishimura T, Tao S, Miyazaki S, Goya M, Sasano T, Haissaguierre M, Jais P. Detailed Analysis of Tachycardia Cycle Length Aids Diagnosis of the Mechanism And Location of Atrial Tachycardias. .Europace. 2023 Jul 10:euad195. doi: 10.1093/europace/euad195.
9. Takigawa M, Yamamoto T, Amemiya M, Martin CA, Ikenouchi T, Yamaguchi J, Negishi M, Goto K, Shigeta T, Nishimura T, Tao S, Miyazaki S, Goya M, Sasano T. Impact of baseline pool impedance on lesion metrics and steam pops in catheter ablation. .J Cardiovasc Electrophysiol. 2023 Jun 19. doi: 10.1111/jce.15964.
10. Tilz RR, Schmidt V, Pürerfellner H, Maury P, Chun KRJU, Martinek M, Sohns C, Schmidt B, Mandel F, Gandjbakhch E, Laredo M, Gunawardene MA, Willems S, Beiert T, Borlich M, Iden L, Füting A, Spittler R, Gaspar T, Richter S, Schade A, Kuniss M, Neumann T, Francke A, Wunderlich C, Shin DI, Meininghaus DG, Foresti M, Bonsels M, Reek D, Wiegand U, Bauer A, Metzner A, Eckardt L, Popescu SȘ, Krahnefeld O, Sticherling C, Kühne M, Nguyen DQ, Roten L, Saguner AM, Linz D, van der Voort P, Mulder BA, Vijgen J, Almorad A, Guenancia C, Fauchier L, Boveda S, Greef Y, Da Costa A, Jais P, Derval N, Milhem A, Jesel L, Garcia R, Poty H, Khoueiry Z, Seitz J, Laborderie J, Mechulan A, Brigadeau F, Zhao A, Saludas Y, Piot O, Ahluwalia N, Martin C, Chen J, Antolic B, Leventopoulos G, Özcan EE, Yorgun H, Cay S, Yalin K, Botros MS, Mahmoud AT, Jędrzejczyk-Patej E, Inaba O, Okumura K, Ejima K, Khakpour H, Boyle N, Catanzaro JN, Reddy V, Mohanty S, Natale A, Blessberger H, Yang B, Stevens I, Sommer P, Veltmann C, Steven D, Vogler J, Kuck KH, Merino JL, Keelani A, Heeger CH A worldwide survey on incidence, management, and prognosis of oesophageal fistula formation following atrial fibrillation catheter ablation: the POTTER-AF study. .Eur Heart J. 2023 Jul 14;44(27):2458-2469. doi: 10.1093/eurheartj/ehad250.
11. Honarbakhsh S, Martin CA, Dhillon G, Gallagher M, Sohal M, Chow A, Ahsan S, Abbass H, Whittaker-Axon S, Lambiase PD, Davies MJ, Ginks M, Hunter RJ. Contact force and catheter stability are predictive metrics of successful pulmonary vein isolation with high-power short duration ablation in atrial fibrillation. J Cardiovasc Electrophysiol. 2023 Feb 17. doi: 10.1111/jce.15867
12. Yamaguchi J, Takigawa M, Goya M, Martin CA, Yamamoto T, Ikenouchi T, Shigeta T, Nishimura T, Tao S, Miyazaki S, Sasano T. Comparison of three different approaches to very high-power short-duration ablation using the QDOT-MICRO catheter. J Cardiovasc Electrophysiol. 2023 Feb 28. doi: 10.1111/jce.15875.
13. Ikenouchi T, Takigawa M, Goya M, Martin CA, Yamamoto T, Yamaguchi J, Goto K, Shigeta T, Nishimura T, Tao S, Miyazaki S, Sasano T. Comparison of lesion characteristics using temperature-flow-controlled versus conventional power-controlled ablation with fixed ablation index. J Cardiovasc Electrophysiol. 2023 Mar 11. doi: 10.1111/jce.15883
14. Martin CA, Tilz RRR, Anic A, Defaye P,Luik A, Carlo de Asmundis C, Laure Champ-Rigot L, Saverio Iacopino S, Philipp Sommer P, Elizabeth M Albrecht EM, Jonathan D Raybuck JD, Elizabeth Richards E , Nele Cielen N, Sing-Chien Yap S-C; POLAR ICE Investigators. Acute procedural efficacy and safety of a novel cryoballoon for the treatment of paroxysmal atrial fibrillation: Results from the POLAR ICE study. J Cardiovasc Electrophysiol. 2023 doi: 10.1111/jce.15861
15. Takigawa M, Martin CA, Yamamoto T, Nakatani Y, Duchateau J, Pambrun T, Derval N, Sacher F, Hocini M, Nishimura T, Tao S, Miyazaki S, Goya M, Haïssaguerre M, Sasano T, Jaïs P. Demonstration of the discrepancy between AT-wave morphology on 12-lead ECG and AT mechanism in scar-related AT. Pacing Clin Electrophysiol. 2023 Jan 23. doi: 10.1111/pace.14665
16. Gupta D, Ding WY, Calvert P, Williams E, Das M, Tovmassian L, Tayebjee MH, Haywood G, Martin CA, Rajappan K, Bates MGD, Temple IP, Reichlin T, Chen Z, Balasubramaniam RN, Ronayne C, Clarkson N, Morgan M, Barton J, Kemp I, Mahida S, Sticherling. Cryoballoon Pulmonary Vein Isolation as First-Line Treatment for Typical Atrial Flutter. Heart. 2022 Nov 17:heartjnl-2022-321729. doi: 10.1136/heartjnl-2022-321729.
17. Ikenouchi T, Takigawa M, Goya M, Martin CA, Takahashi Y, Shimizu Y, Amemiya M, Kamata T, Nishimura T, Tao S, Miyazaki S, Sasano T. Requirement of larger local impedance reduction for successful lesion formation at carinal area during pulmonary vein isolation. J Interv Card Electrophysiol. 2022 Nov;65(2):509-518. doi: 10.1007/s10840-022-01282-1. Epub 2022 Jul 6.PMID: 35794439
18. Honarbakhsh S, Earley MJ, Martin CA, Creta A, Sohaib A, Ang R, Butcher C, Waddingham PH, Dhinoja M, Lim W, Srinivasan NT, Providencia R, Kanthasamy V, Sporton S, Chow A, Lambiase PD, Schilling RJ, Finlay MC, Hunter RJ. PolarX Cryoballoon metrics predicting successful pulmonary vein isolation: targets for ablation of atrial fibrillation. Europace. 2022 Jun 23:euac100. doi: 10.1093/europace/euac100.
19. Schleberger R, Schwarzl JM, Moser J, Nies M, Höller A, Münkler P, Dinshaw L, Jungen C, Lemoine MD, Maury P, Sacher F, Martin CA, Wong T, Estner HL, Jaïs P, Willems S, Eickholt C, Meyer. The impact of ultra-high-density mapping on long-term outcome after catheter ablation of ventricular tachycardia.
C.Sci Rep. 2022 Jun 1;12(1):9139. doi: 10.1038/s41598-022-12918-7.
20. Reddy SA, Nethercott SL, Teh W, De Bie EM, Pepke-Zaba J, Toshner MR, Martin CA. Prevalence and clinical significance of conduction disease in patients with idiopathic pulmonary arterial hypertension.J Heart Lung Transplant. 2022 Jul;41(7):861-865. doi: 10.1016/j.healun.2022.03.024. Epub 2022 Apr 7
21. Amemiya M, Takigawa M, Goya M, Martin CA, Anzai T, Takahashi K, Shimizu Y, Ikenouchi T, Kamata T, Yamamoto T, Nishimura T, Shirai Y, Tao S, Miyazaki S, Sasano T. Comparison of two catheters measuring local impedance: local impedance variation vs lesion characteristics and steam pops..J Interv Card Electrophysiol. 2022 Apr 19. doi: 10.1007/s10840-022-01214-z
22. Frontera A, Limite LR, Pagani S, Cireddu M, Vlachos K, Martin C, Takigawa M, Kitamura T, Bourier F, Cheniti G, Pambrun T, Sacher F, Derval N, Hocini M, Quarteroni A, Della Bella P, Haissaguerre M, Jaïs P. Electrogram fractionation during sinus rhythm occurs in normal voltage atrial tissue in patients with atrial fibrillation. Pacing Clin Electrophysiol. 2021 Dec 16. doi: 10.1111/pace.14425
23. Efremidis M, Vlachos K, Kyriakopoulou M, Mililis P, Martin CA, Bazoukis G, Dragasis S, Megarisiotou A, Unger P, Frontera A, Mascia G, Saplaouras A, Xydonas S, Valkanas K, Sacher F, Jaïs P, Letsas KP. The RV1-V3 transition ratio: A novel electrocardiographic criterion for the differentiation of right versus left outflow tract premature ventricular complexes. Heart Rhythm O2. 2021 Aug 2;2(5):521-528. doi: 10.1016/j.hroo.2021.07.009
24. Takigawa M, Goya M, Iwakawa H, Martin CA, Anzai T, Takahashi K, Kamata T, Matsumura Y, Amemiya M, Yamamoto T, Hirao T, Sekigawa M, Shirai Y, Tao S, Takahashi Y, Sasano T Impact of a formula combining local impedance and conventional parameters on lesion size prediction. J Interv Card Electrophysiol. 2021 Jun 22. doi: 10.1007/s10840-021-01013-y
25. Takigawa M, Kitamura T, Basu S, Bartal M, Martin CA, Martin R, Cheniti G, Vlachos K, Pillois X, Frontera A, Massoullié G, Thompson N, Bourier F, Lam A, Duchateau J, Pambrun T, Denis A, Derval N, Cochet H, Haïssaguerre M, Sacher F, Hocini M, Jaïs P. Effect of electrode size and spacing on electrograms: Optimal electrode configuration for near-field electrogram characterization. Heart Rhythm. 2021 Sep 14:S1547-5271(21)02114-7. doi: 10.1016/j.hrthm.2021.09.011
26. Takigawa M, Takagi T, Martin CA, Derval N, Denis A, Vlachos K, Cheniti G, Duchateau J, Pambrun T, Shirai Y, Tao S, Takahashi Y, Goya M, Sacher F, Cochet H, Hocini M, Haissaguerre M, Sasano T, Jais P. Differentiating atrial tachycardias with centrifugal activation: Lessons from high-resolution mapping. Heart Rhythm. 2021 Jul;18(7):1122-1131. doi: 10.1016/j.hrthm.2021.03.038.
27. Takigawa M, Kitamura T, Martin CA, Fuimaono K, Datta K, Joshi H, Constantin M, Bourier F, Cheniti G, Duchateau J, Pambrun T, Denis A, Derval N, Sacher F, Cochet H, Hocini M, Haïssaguerre M, Jaïs P. Temperature- and flow-controlled ablation/very-high-power short-duration ablation vs conventional power-controlled ablation: Comparison of focal and linear lesion characteristics. Heart Rhythm. 2020 Oct 27:S1547-5271(20)31032-8. doi: 10.1016/j.hrthm.2020.10.021.
28. Iwakawa H, Takigawa M, Goya M, Iwata T, Martin CA, Anzai T, Takahashi K, Amemiya M, Yamamoto T, Sekigawa M, Shirai Y, Tao S, Hayashi T, Takahashi Y, Watanabe H, Sasano T.J Clinical implications of local impedance measurement using the IntellaNav MiFi OI ablation catheter: an ex vivo study. Interv Card Electrophysiol. 2021 Feb 22. doi: 10.1007/s10840-021-00954-8.
29. Honarbakhsh S, Providencia R, Garcia-Hernandez J, Martin CA, Hunter RJ, Lim WY, Kirkby C, Graham AJ, Sharifzadehgan A, Waldmann V, Marijon E, Munoz-Esparza C, Lacunza J, Gimeno-Blanes JR, Ankou B, Chevalier P, Antonio N, Elvas L, Castelletti S, Crotti L, Schwartz P, Scanavacca M, Darrieux F, Sacilotto L, Mueller-Leisse J, Veltmann C, Vicentini A, Demarchi A, Cortez-Dias N, Antonio PS, de Sousa J, Adragao P, Cavaco D, Costa FM, Khoueiry Z, Boveda S, Sousa MJ, Jebberi Z, Heck P, Mehta S, Conte G, Ozkartal T, Auricchio A, Lowe MD, Schilling RJ, Prieto-Merino D, Lambiase PD; Brugada Syndrome Risk Investigators. A Primary Prevention Clinical Risk Score Model for Patients With Brugada Syndrome (BRUGADA-RISK). JACC Clin Electrophysiol. 2021 Feb;7(2):210-222. doi: 10.1016/j.jacep.2020.08.032.
30. Vlachos K, Efremidis M, Derval N, Martin CA, Takigawa M, Bazoukis G, Frontera A, Gkalapis C, Duchateau J, Nakashima T, Letsas KP, Mililis P, Pambrun T, Bourier F, André C, Krisai P, Ramirez FD, Kamakura T, Takagi T, Nakatani Y, Kitamura T, Cheniti G, Sacher F, Hocini M, Haïssaguerre M, Jaïs P. Use of high-density activation and voltage mapping in combination with entrainment to delineate gap-related atrial tachycardias post atrial fibrillation ablation. Europace. 2021 Feb 10:euaa394. doi: 10.1093/europace/euaa394.
