Dr Ian Smith is the Medical Director of Royal Papworth Hospital. He has particular responsibility for the research direction of the hospital. He has led on the delivery of the Heart and Lung Research Institute a major collaboration with the University of Cambridge and oversaw the establishment of the Papworth Clinical Trials Unit.
He is a chest physician specialising in ventilatory failure and sleep medicine with expertise in weaning, domiciliary ventilation, sleep apnoea and non-respiratory sleep disorders including narcolepsy and parasomnias. He led the Hospital’s Respiratory Support and Sleep Centre (RSSC) to be the first in the UK accredited by the European and British Sleep Societies. He was a founder the regional Motor Neurone Disease care network and co-author on the NICE guidelines for people with MND.
In his own research Dr Smith has several grant funded collaborations and has supervised candidates to higher degrees. He is Vice Chair of the UK Association of Respiratory Technicians and Physiologists sleep section. He co-authored the British Thoracic Society position statement on driving and sleep apnoea. Dr Smith is an Affiliated Associate Professor to the University of Cambridge and has held a number of key educational posts locally and across the Eastern Region.
Home ventilation, sleep disorders, sleep apnoea, motor neurone disease (MND).
Treatment of sleep apnoea, Home ventilation, Respiratory failure in MND, Weaning from invasive ventilation.
Exhibition to Gonville and Caius College Cambridge
BA (Hons) Medical Sciences
MA March 1988
MBBS July 1987
MRCP (London) June 1990
MD (Cambridge University) March 1997
FRCP (London) 2000
ARTP award for services to Respiratory Medicine 2016
Fellow of the Royal College of Physicians
Registered with the GMC no.3201378
Associate Lecturer Cambridge University
Member of British Thoracic Society
Member of European Respiratory Society
Davies MG, Wozniak DR, Quinnell TG, Palas E, George S, Huang Y, Jayasekara R, Stoneman V, Smith IE, Thomsen LP, Rees SE. Comparison of mathematically arterialised venous blood gas sampling with arterial, capillary, and venous sampling in adult patients with hypercapnic respiratory failure: a single-centre longitudinal cohort study. BMJ Open Respir Res. 2023
Marciniak SJ, Farrell J, Rostron A, Smith I, Openshaw PJM, Baillie JK, Docherty A, Semple MG. COVID-19 pneumothorax in the UK: a prospective observational study using the ISARIC WHO clinical characterisation protocol. Eur Respir J. 2021; 58
Martinelli AW, Ingle T, Newman J, Nadeem I, Jackson K, Lane ND, Melhorn J, Davies HE, Rostron AJ, Adeni A, Conroy K, Woznitza N, Matson M, Brill SE, Murray J, Shah A, Naran R, Hare SS, Collas O, Bigham S, Spiro M, Huang MM, Iqbal B, Trenfield S, Ledot S, Desai S, Standing L, Babar J, Mahroof R, Smith I, Lee K, Tchrakian N, Uys S, Ricketts W, Patel ARC, Aujayeb A, Kokosi M, Wilkinson AJK, Marciniak SJ. COVID-19 and pneumothorax: a multicentre retrospective case series. Eur Respir J. 2020;56
Askland K, Wright L, Wozniak DR, Emmanuel T, Caston J, Smith I. Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database of Systematic Reviews 2020, Issue 4.
Wozniak DR, Bourne RR, Peretz G, Kean J, Willshire C, Harun, S, Villar SS, Chiu Y, Smith IE. Obstructive Sleep Apnea in Patients With Primary-open Angle Glaucoma: No Role for a Screening Program. Journal of Glaucoma 2019, 28, 668 - 675
Kennedy B, Lasserson TJ, Wozniak DR, Smith I. Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database of Systematic Reviews 2019, Issue 12.
PB Murphy, S Rehal, G Arbane, S Bourke, ; PMA Calverley, AM Crook, L Dowson, N Duffy, GJ Gibson, PD Hughes, JR Hurst, K E Lewis, R Mukherjee, A Nickol, N Oscroft, M Patout, J Pepperell, I Smith, JR Stradling, JA Wedzicha, MI Polkey, MW Elliott, N Hart, Effect of Home Noninvasive Ventilation with Oxygen Therapy vs Oxygen Therapy alone on hospital readmission or death after an acute COPD exacerbation, a randomized clinical trial. JAMA 2017; 317: 2177-2186
Davies MG, Quinnell TG, Oscroft NS, Clutterbuck SP, Shneerson JM, Smith IE. Hospital outcomes and long-term survival after referral to a specialized weaning unit. Br J Anaesth 2017; 118: 563-569
M Mason, J Hernadez Sanchez, A Vuylsteke, I Smith. Association between the severity of untreated sleep apnoea and postoperative complications following major cardiac surgery: a prospective observational cohort study. Sleep Medicine 2017; 37: 141-146
Gulati A, Oscroft N, Chadwick R, Ali M, Smith I. The impact of changing people with sleep apnea using CPAP less than 4 h per night to a Bi-level device. Respir Med 2015; 109: 778-783.
Mason M, Cates CJ, Smith I. Effects of opioid, hypnotic and sedating medications on sleep-disordered breathing in adults with obstructive sleep apnoea. Cochrane Database of Systematic Reviews 2015.
Oscroft NS, Chadwick R, Davies MG, Quinnell TG, Smith IE. Volume assured versus pressure preset non-invasive ventilation for compensated ventilatory failure in COPD. Respir Med 2014; 108: 1508-1515
Quinnell TG, Bennett M, Jordan J, Clutterbuck-James AL, Davies MG, Smith IE, Oscroft N, Pittman MA, Cameron M, Chadwick R, Morrell MJ, Glover MJ, Fox-Rushby JA, Sharples LD. A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO). Thorax 2014; 69: 938-945
Mason M, Welsh E, Smith I. Drug therapy for sleep apnoea in adults. Cochrane Database of Systematic Reviews 2013
Randerath WJ, Verbraecken J, Andreas S, Bettega G, Boudewyns A, Hamans E, Jalbert F, Paoli JR, Sanner B, Smith I, Stuck BA, Lacassagne L, Marklund M, Maurer JT, Pepin JL, Valipour A, Verse T, Fietze I. Non-CPAP therapies in obstructive sleep apnoea. Eur Respir J 2011; 37:1000-1028
Oscroft NS, Quinnell TG, Shneerson JM, Smith IE. Long-term non-invasive ventilation to manage persistent ventilatory failure after COPD exacerbation. Respirology. 2010;15:818-22.
