Dr Begley is a consultant cardiologist and specialist in cardiac rhythm management at Royal Papworth Hospital. He was appointed Clinical Director for Cardiology in September 2018.

He graduated from the University of Edinburgh in 1994. Following a period of general training in Scotland, he completed a period of clinical research in hypertrophic cardiomoypathy at the National Institutes of Health in Bethesda, Maryland, USA and was awarded the degree of Doctor of Medicine by the University of Edinburgh.
He trained in general cardiology in the northern rotation based at the Freeman Hospital in Newcastle and James Cook University Hospital in Middlesbrough where he completed subspecialty training in cardiac electrophysiology and device therapy. He was appointed a consultant at Papworth in 2007. He was clinical lead for cardiac electrophysiology and device therapy between 2011 and 2016.

He has extensive experience in all aspects of adult cardiac electrophysiology including the ablation of complex arrhythmias, device implantation, extraction techniques. Special interests include the ablation of ventricular tachycardias related to ischaemic heart disease and cardiomyopathies. His research interests are related to the ablation of complex arrhythmias.

He is heavily involved in medical education at all levels and is currently Undergraduate Program Director in Cardiology, educational supervisor for foundation trainees, University of Cambridge Senior Clinical Tutor. In addition, he has been involved with the British Heart Rhythm Society Accreditation Examination Committee since it was significantly revised in 2010.

Specialties

Cardiac Electrophysiology and Device Therapy.

Specialist Clinical Interests

Arrhythmias, radiofrequency ablation, pacemakers, implantable defibrillators and cardiac resynchronization therapy.

Research Interests

Arrhythmias, radiofrequency ablation.

Education and Training

MB ChB 1994 
MRCP (UK) 1997 
MD 2008
FRCP (Edin) 2008

Current membership(s) of professional, national and regional bodies and university posts

Fellow of the Royal College of Physicians, Edinburgh.
Senior Clinical Tutor, University of Cambridge.
Royal College Tutor
British Cardiovascular Society
British Heart Rhythm Society
European Society of Cardiology

Recent and Important Publications

Barra S, Providencia R, Duehmke R, Boveda S, Begley D, Grace A, Narayanan K, Tang A, Marijon E and Agarwal S. Cause-of-death analysis in patients with cardiac resynchronization therapy with or without a defibrillator: a systematic review and proportional meta-analysis. Europace. 2018;20:481-491.

 

Barra S, Duehmke R, Providencia R, Marijon E, Boveda S, Virdee M, Heck P, Fynn S, Begley D, Grace A and Agarwal S. Patients upgraded to cardiac resynchronization therapy due to pacing-induced cardiomyopathy are at low risk of life-threatening ventricular arrhythmias: a long-term cause-of-death analysis. Europace. 2018;20:89-96.

 

Martin CA, Curtain JP, Gajendragadkar PR, Begley DA, Fynn SP, Grace AA, Heck PM, Salaunkey K, Virdee MS and Agarwal S. Improved outcome and cost effectiveness in ablation of persistent atrial fibrillation under general anaesthetic. Europace. 2017.

 

Barra S, Providencia R, Duehmke R, Boveda S, Marijon E, Reitan C, Borgquist R, Klug D, Defaye P, Sadoul N, Deharo JC, Sadien I, Patel K, Looi KL, Begley D, Chow AW, Le Heuzey JY, Agarwal S and French UKSCRTN. Sex-specific outcomes with addition of defibrillation to resynchronisation therapy in patients with heart failure. Heart. 2017.

 

Barra S, Providencia R, Duehmke R, Boveda S, Begley D, Grace A, Narayanan K, Tang A, Marijon E and Agarwal S. Cause-of-death analysis in patients with cardiac resynchronization therapy with or without a defibrillator: a systematic review and proportional meta-analysis. Europace. 2017.

 

Barra S, Goonewardene M, Heck P, Begley D, Virdee M, Fynn S, Grace A and Agarwal S. Implantable cardioverter-defibrillator elective generator replacement: a procedure for all? Journal of interventional cardiac electrophysiology. 2016;45:209-18.

 

Barra S, Duehmke R, Providencia R, Marijon E, Boveda S, Virdee M, Heck P, Fynn S, Begley D, Grace A and Agarwal S. Patients upgraded to cardiac resynchronization therapy due to pacing-induced cardiomyopathy are at low risk of life-threatening ventricular arrhythmias: a long-term cause-of-death analysis. Europace. 2016.

 

Looi KL, Gajendragadkar P, Taha T, Elsik M, Scully E, Heck P, Fynn S, Virdee M and Begley D. Long-term outcomes (>2 years) of atrial fibrillation ablation using a multi-electrode ablation catheter in patients with paroxysmal atrial fibrillation. Journal of interventional cardiac electrophysiology. 2013;36:61-9; discussion 69.

 

Khan FZ, Virdee MS, Palmer CR, Pugh PJ, O'Halloran D, Elsik M, Read PA, Begley D, Fynn SP and Dutka DP. Targeted left ventricular lead placement to guide cardiac resynchronization therapy: the TARGET study: a randomized, controlled trial. J Am Coll Cardiol. 2012;59:1509-18.

 

Khan FZ, Virdee MS, Begley D, Hutchinson J, Smith B, Read PA, Pugh PJ, Fynn SP and Dutka DP. Acute non-invasive cardiac output measurements following cardiac resynchronization therapy predict left ventricular remondelling at 6 months and long term survival. J Am Coll Cardiol. 2011;57:E96-E96.

 

Begley DA, Mohiddin SA, Tripodi D, Winkler JB and Fananapazir L. Efficacy of implantable cardioverter defibrillator therapy for primary and secondary prevention of sudden cardiac death in hypertrophic cardiomyopathy. Pacing and clinical electrophysiology : PACE. 2003;26:1887-96.

 

Gollob MH, Green MS, Tang AS, Gollob T, Karibe A, Ali Hassan AS, Ahmad F, Lozado R, Shah G, Fananapazir L, Bachinski LL, Begley D, Mohiddin S and Roberts R. Identification of a gene responsible for familial Wolff-Parkinson-White syndrome. The New England journal of medicine. 2001;344:1823-31.

 

Begley D, Mohiddin S and Fananapazir L. Dual chamber pacemaker therapy for mid-cavity obstructive hypertrophic cardiomyopathy. Pacing and clinical electrophysiology : PACE. 2001;24:1639-44.

Where are we based?

Royal Papworth Hospital NHS Foundation Trust
Papworth Road
Cambridge Biomedical Campus
Cambridge
CB2 0AY

Telephone:  01223 638000

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